What are the common histopathologic patterns seen in canine inflammatory bowel disease?

• A. Lymphoplasmacytic enteritis, eosinophilic enteritis, and granulomatous enteritis.
• B. Acute neutrophilic hepatitis.
• C. Lymphocytic enteritis and plasma cell infiltrates.
• D. Chronic pancreatitis with acinar atrophy.

Answer: (A)

Histopathology of canine inflammatory bowel disease is categorized by the predominant inflammatory cell types in the intestinal mucosa. The classic patterns you’ll see are lymphoplasmacytic enteritis (where lymphocytes and plasma cells dominate the lamina propria), eosinophilic enteritis (eosinophils are the main inflammatory cells), and granulomatous enteritis (granulomatous inflammation with macrophages). Lymphoplasmacytic enteritis is the most common form, while eosinophilic and granulomatous forms are recognized variants seen in dogs, often linked to allergic/food-responsive disease or other etiologies, respectively. The other choices don’t reflect intestinal histopathology: one describes a liver condition, another involves the pancreas, and another describes a partial pattern that doesn’t include the eosinophilic or granulomatous forms.